Find out more about the gas mileage of the Mercedes-Benz E 350 for 2022 at Mercedes-Benz of Boerne.
The 2022 Mercedes-Benz E 350 is one more crown jewel from the E-Class series of Mercedes-Benz. The 2022 E 350 is available in two models; the base E 350 and the E 350 4MATIC®. Every year the E-Class Sedan advances the standards for all cars to follow, from luxury, safety, and driver-assist technology to less time at the gas pump. Boasting newly enhanced innovations in a new way like the Mercedes-Benz built-in Emergency Call Service, the 2022 Mercedes-Benz E 350 is the next generation of luxury today.
READ MORE: What is EPA MPG?
| Miles Per Gallon of the 2022 Mercedes-Benz E 350 | ||||
|---|---|---|---|---|
| Trim Levels | MPG | Gas Tank Size | Engine Specs | |
| E 350 4MATIC® | 23 City, 30 Highway | 17.4 Gallons | 255 Horsepower, 2.0L Turbocharged 4-cylinder | |
| E 350 | 23 City, 31 Highway | 17.4 Gallons | 255 Horsepower, 2.0L Turbocharged 4-cylinder | |
The brand-new Mercedes-Benz E 350 has a 17.4-gallon gas tank size for both the base E 350 and E 350 4MATIC® models. When you combine this ample gasoline tank size with the ECO-START® system, you get more out of the fuel tank. Plus, there are four different driving modes: ECO, Comfort, Sport, and Sport+ to customize the E 350 however you want.
The 2022 Mercedes-Benz E 350 should have more than 530 miles of max range on a single tank of gas. This comes from the estimated mileage numbers of the base E 350, which is expected to return 23 city mpg and 31 highway mpg, which makes for a combined 27mpg. In comparison, the 4MATIC® model is expected to get 21 city miles per gallon and 29 highway mpg, making for a combined 25mpg. No matter what model you select, you’re going to get a lot from the new 2022 Mercedes-Benz E 350.
The new Mercedes-Benz E 350 is equipped with a 2.0-liter turbo 4-cylinder engine for the standard and optional 4MATIC® trim level. A 9G-TRONIC 9-speed automatic is equipped in both options. The base E 350 utilizes RWD, while the E 350 4MATIC® uses 4MATIC® all-wheel drive. The 2022 E 350 engine will take you from 0-60 in 6 seconds, while the E 350 4MATIC® comes in at 6 seconds flat. Both trim levels create 255 hp and 273 lb.-ft. of torque. If you’re in the market for the next-gen of luxury vehicles, the 2022 Mercedes-Benz E 350 is the sedan you’ve been waiting for.
Learn more about the 2022 E 350 at our Mercedes-Benz dealership near San Antonio. Visit us in person or online to schedule your test drive. Our helpful staff is standing by to help you get into the luxury car or SUV of your dreams.
Descubre el Mercedes-Benz E 350 cerca de San Antonio, TX. Si, se habla español. Visítanos hoy.
2022 Mercedes-Benz E 350 MPG | Mercedes-Benz of Boerne
Quick and easy! I had the wrong day and they still got me in with no problems!
This location has associates who care about the customer and are willing to be of assistance. I generally have costly repair to my vehicle and they never made me feel as if I was just another dollar walking through the door. This location really does a good job of seeing the person behind the wheel to this point in our journey.
I could not be more pleased! Incredible helpful , I feel so very well taken care off! I like the way this Company communicates with me. My service adviser is absolutely wonderful! Thank you Eddy!
Good communication, good customer service, good mechanical service. I know this dealership takes extra care and presents all options.
Emergency roadside repair needed driving through Boerne, Tx. Road debris punctured a hole in our battery radiator which was leaking coolant. They replaced it ($2500), were efficient and informative with the work. Must give Javier Rojas honorable mention. He took great care of us, helping us with luggage to and from a rental car (since we needed to stay overnight), was very attentive and informative. Another unnamed valet there refused to assist, ignored us and when his assistance was requested, refused to do so. He was busy scrolling through his phone. We brought this to the dealer's attention with hopes ... Read More Full review text opened.DealerRater - Sep 19, 2026
Emergency roadside repair needed driving through Boerne, Tx. Road debris punctured a hole in our battery radiator which was leaking coolant. They replaced it ($2500), were efficient and informative with the work. Must give Javier Rojas honorable mention. He took great care of us, helping us with luggage to and from a rental car (since we needed to stay overnight), was very attentive and informative. Another unnamed valet there refused to assist, ignored us and when his assistance was requested, refused to do so. He was busy scrolling through his phone. We brought this to the dealer's attention with hopes for improvement. Loved the video tech analysis, but had a long wait for the loaner car. Seems they forgot about us until I had to press them.
The service bay was meticulous.
Overall, we are grateful for their working our emergency into their existing schedule and mention the negatives only to help them improve in those areas.
