Find out more about the gas mileage of the Mercedes-Benz E 350 for 2022 at Mercedes-Benz of Boerne.
The 2022 Mercedes-Benz E 350 is one more crown jewel from the E-Class series of Mercedes-Benz. The 2022 E 350 is available in two models; the base E 350 and the E 350 4MATIC®. Every year the E-Class Sedan advances the standards for all cars to follow, from luxury, safety, and driver-assist technology to less time at the gas pump. Boasting newly enhanced innovations in a new way like the Mercedes-Benz built-in Emergency Call Service, the 2022 Mercedes-Benz E 350 is the next generation of luxury today.
READ MORE: What is EPA MPG?
| Miles Per Gallon of the 2022 Mercedes-Benz E 350 | ||||
|---|---|---|---|---|
| Trim Levels | MPG | Gas Tank Size | Engine Specs | |
| E 350 4MATIC® | 23 City, 30 Highway | 17.4 Gallons | 255 Horsepower, 2.0L Turbocharged 4-cylinder | |
| E 350 | 23 City, 31 Highway | 17.4 Gallons | 255 Horsepower, 2.0L Turbocharged 4-cylinder | |
The brand-new Mercedes-Benz E 350 has a 17.4-gallon gas tank size for both the base E 350 and E 350 4MATIC® models. When you combine this ample gasoline tank size with the ECO-START® system, you get more out of the fuel tank. Plus, there are four different driving modes: ECO, Comfort, Sport, and Sport+ to customize the E 350 however you want.
The 2022 Mercedes-Benz E 350 should have more than 530 miles of max range on a single tank of gas. This comes from the estimated mileage numbers of the base E 350, which is expected to return 23 city mpg and 31 highway mpg, which makes for a combined 27mpg. In comparison, the 4MATIC® model is expected to get 21 city miles per gallon and 29 highway mpg, making for a combined 25mpg. No matter what model you select, you’re going to get a lot from the new 2022 Mercedes-Benz E 350.
The new Mercedes-Benz E 350 is equipped with a 2.0-liter turbo 4-cylinder engine for the standard and optional 4MATIC® trim level. A 9G-TRONIC 9-speed automatic is equipped in both options. The base E 350 utilizes RWD, while the E 350 4MATIC® uses 4MATIC® all-wheel drive. The 2022 E 350 engine will take you from 0-60 in 6 seconds, while the E 350 4MATIC® comes in at 6 seconds flat. Both trim levels create 255 hp and 273 lb.-ft. of torque. If you’re in the market for the next-gen of luxury vehicles, the 2022 Mercedes-Benz E 350 is the sedan you’ve been waiting for.
Learn more about the 2022 E 350 at our Mercedes-Benz dealership near San Antonio. Visit us in person or online to schedule your test drive. Our helpful staff is standing by to help you get into the luxury car or SUV of your dreams.
Descubre el Mercedes-Benz E 350 cerca de San Antonio, TX. Si, se habla español. Visítanos hoy.
2022 Mercedes-Benz E 350 MPG | Mercedes-Benz of Boerne
The entire service dept goes above and beyond. The waiting area is spotless and comfortable snacks are a nice addition. David has been my service advisor since we purchased our first wagon and is the best of the best!
Excellent service! Friendly staff, prompt repairs, and top-notch attention to detail. Mercedes Boerne truly delivers a premium experience every time. Highly recommended!
Excellent service provided by Linda de la Cruz! Professional, and gave me updates as she knew more about the car problems.
Great customer service. Mr Chris Forbes was knowledgeable and professional helping me make a decision on the tires I needed.
They washed the car and there were hard water spots on the entire car. Took me 1.5 hrs to get them off. Not very happy. The passenger headrest was all the way up and I couldn't figure out how to get it back down. Told our service advisor and he explained where the button was but i didn't see what he said it looked like. Went back inside to see him again but he was with a customer. Finally the lady at the loaner vehicle counter went out to my car and figured it out. Our service advisor should ... Read More Full review text opened.DealerRater - Jun 10, 2025
They washed the car and there were hard water spots on the entire car. Took me 1.5 hrs to get them off. Not very happy. The passenger headrest was all the way up and I couldn't figure out how to get it back down. Told our service advisor and he explained where the button was but i didn't see what he said it looked like. Went back inside to see him again but he was with a customer. Finally the lady at the loaner vehicle counter went out to my car and figured it out. Our service advisor should have done that.
(830) 981-6000
Call Now31445 I-10 • Boerne, TX 78006
Get DirectionsOpen Today! Sales: 8:30am-6pm
Open Today! Service: 7am-6pm
Open Today! Parts: 7am-6pm
