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31445 I-10, Boerne, TX, 78006

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  • Mon - Sun12:00 AM - 12:00 AM
    (Always Open for Online Shopping)
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  • Mon - Fri8:30 AM - 7:00 PM
  • Sat8:30 AM - 6:00 PM
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  • Mon - Sat7:00 AM - 6:00 PM
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2022 Mercedes-Benz E 350 MPG

2022 mercedes-benz e 350 mpg

What is the MPG of the Mercedes-Benz E 350 for 2022?

Find out more about the gas mileage of the Mercedes-Benz E 350 for 2022 at Mercedes-Benz of Boerne.

The 2022 Mercedes-Benz E 350 is one more crown jewel from the E-Class series of Mercedes-Benz. The 2022 E 350 is available in two models; the base E 350 and the E 350 4MATIC®. Every year the E-Class Sedan advances the standards for all cars to follow, from luxury, safety, and driver-assist technology to less time at the gas pump. Boasting newly enhanced innovations in a new way like the Mercedes-Benz built-in Emergency Call Service, the 2022 Mercedes-Benz E 350 is the next generation of luxury today.


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READ MORE: What is EPA MPG?


Miles Per Gallon of the 2022 Mercedes-Benz E 350
Trim Levels MPG Gas Tank Size Engine Specs
E 350 4MATIC® 23 City, 30 Highway 17.4 Gallons 255 Horsepower, 2.0L Turbocharged 4-cylinder
E 350 23 City, 31 Highway 17.4 Gallons 255 Horsepower, 2.0L Turbocharged 4-cylinder


2022 E 350 Fuel Tank Capacity

Mercedes-Benz E 350 Fuel Tank Capacity

The brand-new Mercedes-Benz E 350 has a 17.4-gallon gas tank size for both the base E 350 and E 350 4MATIC® models. When you combine this ample gasoline tank size with the ECO-START® system, you get more out of the fuel tank. Plus, there are four different driving modes: ECO, Comfort, Sport, and Sport+ to customize the E 350 however you want.

 How Far Can the 2022 E 350 Go On a Tank of Gas?

How Far Can the 2022 Mercedes-Benz E 350 Go On a Tank of Gas?

The 2022 Mercedes-Benz E 350 should have more than 530 miles of max range on a single tank of gas. This comes from the estimated mileage numbers of the base E 350, which is expected to return 23 city mpg and 31 highway mpg, which makes for a combined 27mpg. In comparison, the 4MATIC® model is expected to get 21 city miles per gallon and 29 highway mpg, making for a combined 25mpg. No matter what model you select, you’re going to get a lot from the new 2022 Mercedes-Benz E 350.

What is the Engine Performance of the Mercedes-Benz E 350?

What is the Engine Performance of the E 350?

The new Mercedes-Benz E 350 is equipped with a 2.0-liter turbo 4-cylinder engine for the standard and optional 4MATIC® trim level. A 9G-TRONIC 9-speed automatic is equipped in both options. The base E 350 utilizes RWD, while the E 350 4MATIC® uses 4MATIC® all-wheel drive. The 2022 E 350 engine will take you from 0-60 in 6 seconds, while the E 350 4MATIC® comes in at 6 seconds flat. Both trim levels create 255 hp and 273 lb.-ft. of torque. If you’re in the market for the next-gen of luxury vehicles, the 2022 Mercedes-Benz E 350 is the sedan you’ve been waiting for.


Mercedes-Benz online car buying San Antonio TX

Experience the 2022 Mercedes-Benz E 350 at Mercedes-Benz of Boerne

Learn more about the 2022 E 350 at our Mercedes-Benz dealership near San Antonio. Visit us in person or online to schedule your test drive. Our helpful staff is standing by to help you get into the luxury car or SUV of your dreams.


Descubre el Mercedes-Benz E 350 cerca de San Antonio, TX. Si, se habla español. Visítanos hoy.


2022 Mercedes-Benz E 350 MPG | Mercedes-Benz of Boerne

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DealerRater Aug 14, 2026

They have always provided great service. Never had any issues at all. Everyone is great.

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DealerRater Aug 10, 2026

Charles Spencer was our Service Advisor last week.. Charles was friendly, professional, articulate and knowledgeable. He did a great job educating us on our maintenance schedule work and also was very helpful with all of our questions. I will ask for Charles to be our Service Advisor on our next scheduled maintenance. Thank you Charles!

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DealerRater Aug 7, 2026

Efficient, friendly and honest, good communicator expensive but thorough with my safety their primary concern

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DealerRater Aug 7, 2026

I have had some really bad experiences at this dealership in the past, and quite honestly, at other dealerships as well. I’m writing this because of the exceptional service I received from Master Sprinter Technician Kenny Dieurestil and Sprinter Service Advisor Rick Caldera. They promised me they would take care of our service van, and they delivered. I gave Mercedes-Benz of Georgetown two previous attempts to diagnose and repair a coolant leak on our 2024 Sprinter Cargo Work Van. Both times, they kept the van for three days and then four days, yet they could not find or fix the ... Read More

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DealerRater Aug 5, 2026

Staff was very attentive and focused on our needs. Will continue to purchase vehicles from them

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Mercedes-Benz of Boerne 29.7915419, -98.7496179.